466: Magnesium for neuroprotection at the borderline of viability

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Different magnesium sulphate regimens for neuroprotection of the fetus for women at risk of preterm birth.

BACKGROUND The effectiveness of antenatal magnesium sulphate for neuroprotection of the fetus, infant, and child prior to very preterm birth, when given to women considered at risk of preterm birth, has been established. There is currently no consensus as to the regimen to use in terms of the dose, duration, the use of repeat dosing and timing. OBJECTIVES To assess the comparative effectivene...

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Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.

BACKGROUND Epidemiological and basic science evidence suggests that magnesium sulphate before birth may be neuroprotective for the fetus. OBJECTIVES To assess the effectiveness and safety of magnesium sulphate as a neuroprotective agent when given to women considered at risk of preterm birth. SEARCH STRATEGY We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (October ...

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Magnesium sulphate for women at term for neuroprotection of the fetus.

BACKGROUND Magnesium sulphate is extensively used in obstetrics for the treatment and prevention of eclampsia. A recent meta-analysis has shown that magnesium sulphate is an effective fetal neuroprotective agent when given antenatally to women at risk of very preterm birth. Term infants account for more than half of all cases of cerebral palsy, and the incidence has remained fairly constant. It...

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ژورنال

عنوان ژورنال: American Journal of Obstetrics and Gynecology

سال: 2020

ISSN: 0002-9378

DOI: 10.1016/j.ajog.2019.11.482